Collaborative ocular melanoma study

Collaborative Ocular Melanoma Study

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The Collaborative Ocular Melanoma Study Multicenter randomized trials sponsored by: The National Eye Institute and The National Cancer Institute of The National Institutes of Health: U.S. Department of Health and Human Services

Collaborative Ocular Melanoma Study

Collaborative Ocular Melanoma Study (COMS) » New York Eye ...

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Small-sized Choroidal Melanoma Study Small melanomas can be watched for growth prior to treatment. Should growth occur, then the patient knows the melanoma will eventually destroy the vision and increase the chance that cancer cells will spread to other parts of the body. The Collaborative Ocular Melanoma Study (COMS) was interested in how many small [..]

Collaborative Ocular Melanoma Study (COMS) » New York Eye ...

The Collaborative Ocular Melanoma Study: An Overview

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Background: The Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for treatment of medium-size choroidal melanomas, and the effectiveness of enucleation with and without preoperative ...

The Collaborative Ocular Melanoma Study: An Overview

Collaborative Ocular Melanoma Study (COMS) - Full Text ...

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The Collaborative Ocular Melanoma Study (COMS) is a set of long-term, multicenter, randomized controlled trials. In the trial for patients with tumors of medium size, enucleation and irradiation with an iodine-125 episcleral plaque are compared on the basis of length of remaining life.

Collaborative Ocular Melanoma Study (COMS) - Full Text ...

The Collaborative Ocular Melanoma Study (COMS) randomized ...

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Hawkins BS(1); Collaborative Ocular Melanoma Study Group. Author information: (1)bhawkins@jhmi.edu PURPOSE: To report rates of death and related outcomes through 10 years after treatment of large choroidal melanoma and to evaluate characteristics of patients and tumors as predictors of relative treatment effectiveness and time to death.

The Collaborative Ocular Melanoma Study (COMS) randomized ...

Collaborative Ocular Melanoma Study (COMS) - Publications ...

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The Collaborative Ocular Melanoma Study Dr. Finger is a Principal Investigator in the Collaborative Ocular Melanoma Study Group Collaborative Ocular Melanoma Study Publications: Peer-review papers only. 1. Collaborative Ocular Melanoma Study Group: Accuracy of diagnosis of choroidal melanomas in the Collaborative Ocular Melanoma Study. COMS Report No. 1.

Collaborative Ocular Melanoma Study (COMS) - Publications ...

Collaborative ocular melanoma study (COMS) randomized ...

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DESIGN: Observational case series within a randomized, multicenter study. PARTICIPANTS: Patients enrolled in the Collaborative Ocular Melanoma Study randomized trial of I(125) brachytherapy versus enucleation had choroidal melanoma of at least 2.5 mm but no more than 10.0 mm in apical height, and no more than 16.0 mm in largest basal dimension.

Collaborative ocular melanoma study (COMS) randomized ...

Collaborative Ocular Melanoma Study (COMS) - No Study ...

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Collaborative Ocular Melanoma Study Group. Incidence of cataract and outcomes after cataract surgery in the first 5 years after iodine 125 brachytherapy in the Collaborative Ocular Melanoma Study: COMS Report No. 27. Ophthalmology. 2007 Jul;114(7):1363-71. Epub 2007 Mar 6.

Collaborative Ocular Melanoma Study (COMS) - No Study ...

Collaborative ocular melanoma study (COMS) randomized ...

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The Collaborative Ocular Melanoma Study (COMS) is a set of multicenter clinical trials initiated in 1986 to address the role of radiotherapy versus enucleation with respect to long-term survival in selected patients with choroidal melanoma.

Collaborative ocular melanoma study (COMS) randomized ...

The Collaborative Ocular Melanoma Study: An Overview

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The Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for ...

The Collaborative Ocular Melanoma Study: An Overview

The Collaborative Ocular Melanoma Study: An Overview ...

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BackgroundThe Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for treatment of medium-size choroidal melanomas, and the effectiveness of enucleation with and without preoperative external-beam radiotherapy for large choroidal melanomas.

The Collaborative Ocular Melanoma Study: An Overview ...

The Collaborative Ocular Melanoma Study - ResearchGate

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The Collaborative Ocular Melanoma Study - ResearchGate

The Collaborative Ocular Melanoma Study - ResearchGate

Legacy of the Collaborative Ocular Melanoma Study Z

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Legacy of the Collaborative Ocular Melanoma Study Bertil Damato, MD, PhD, FRCOphth Z ... The Collaborative Ocular Melanoma Study (COMS) ... The articles that follow are part of an ongoing series that aims to review collaborative prospective studies supported by the National Eye Institute. The first article, written by investigators, will remind ...

Legacy of the Collaborative Ocular Melanoma Study Z

Collaborative Ocular Melanoma Study | Clinical Gate

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The Collaborative Ocular Melanoma Study (COMS) was the first set of randomized clinical trials designed and conducted with sufficient power to compare survival outcomes between two or more treatments for this primary ocular cancer with a high degree of confidence.

Collaborative Ocular Melanoma Study | Clinical Gate

Design and methods of a clinical trial for a rare ...

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Design and Methods of a Clinical Trial for a Rare Condition: The Collaborative Ocular Melanoma Study COMS Report No. 3 The Collaborative Ocular Melanoma Study Group's ABSTRACT: Investigators who conduct clinical trials of treatments for uncommon conditions face special challenges regarding trial design and execution in addition to the challenges faced by all clinical trial investigators.

Design and methods of a clinical trial for a rare ...

Uveal melanoma - Wikipedia

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The treatment protocol for uveal melanoma has been directed by many clinical studies, the most important being The Collaborative Ocular Melanoma Study (COMS). The treatment varies depending upon many factors, chief among them, the size of the tumor …

Uveal melanoma - Wikipedia

Cancer Research — The Collaborative Ocular Melanoma Study

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9/20/2018 · Retina Associates, a clinic providing ocular care to patients residing in and near Tucson, Arizona, participated in the Collaborative Ocular Melanoma Study (COMS). In fact, Retina Associates and ...

Cancer Research — The Collaborative Ocular Melanoma Study

Histopathologic characteristics of uveal melanomas in eyes ...

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Albert DM, Diener-West M, Robinson NL, Grossniklaus HE, Green WR, Vine AK et al. Histopathologic characteristics of uveal melanomas in eyes enucleated from the collaborative ocular melanoma study COMS report no. 6.

Histopathologic characteristics of uveal melanomas in eyes ...

Collaborative Ocular Melanoma Quality Of Life Study

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Welcome to the Collaborative Ocular Melanoma Quality Of Life Study The Quality of Life Study was added as a component of the COMS in 1995. It is designed to measure the effect of choroidal melanoma on health- and vision- related quality of life and to determine whether quality of life differs in patients who are treated by radiation (I-125 plaque) versus enucleation (removal of the eye).

Collaborative Ocular Melanoma Quality Of Life Study

The Collaborative Ocular Melanoma Study: an overview.

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BACKGROUND: The Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for treatment of medium-size choroidal melanomas, and the effectiveness of enucleation with and without preoperative external-beam radiotherapy ...

The Collaborative Ocular Melanoma Study: an overview.

Collaborative Ocular Melanoma Study randomized trial of I ...

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TY - JOUR. T1 - Collaborative Ocular Melanoma Study randomized trial of I-125 brachytherapy. AU - Hawkins, Barbara S. PY - 2011/10. Y1 - 2011/10

Collaborative Ocular Melanoma Study randomized trial of I ...

Management of Choroidal Melanoma and Ciliary Body Melanoma ...

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The Collaborative Ocular Melanoma Study (COMS) was designed to evaluate management of choroidal melanoma in a prospective fashion. The COMS conducted three multicenter trials including: the large choroidal melanoma trial comparing enucleation versus enucleation preceded by external beam radiotherapy, the medium choroidal melanoma trial ...

Management of Choroidal Melanoma and Ciliary Body Melanoma ...

Choroidal Melanoma - nyee.edu

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The Collaborative Ocular Melanoma Study What you need to know! -- By Paul T. Finger, MD The COMS offers the best evidence based medicine available about the diagnosis and treatment of choroidal melanoma. Page 3 Treatment Arms Small Choroidal Melanoma …

Choroidal Melanoma - nyee.edu

OMF - Primary Treatment - Ocular Melanoma

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The treatment of the primary tumor in ocular melanoma has evolved quite dramatically over the past many years and has also been directed by numerous clinical studies including "The Collaborative Ocular Melanoma Study (COMS).”The treatment of metastatic disease continues to require more research to determine what the most effective, and life saving, treatments may be.

OMF - Primary Treatment - Ocular Melanoma

Collaborative Ocular Melanoma Study randomized trial of I ...

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Background Although findings from observational studies published in the 1970s and early 1980s suggested that length of remaining life after a diagnosis of uveal melanoma was similar following enucleation (removal of the eye) and local eye-conserving radiotherapy, the majority of ophthalmologists in the United States were not convinced that “saving the eye” would not compromise survival ...

Collaborative Ocular Melanoma Study randomized trial of I ...

Ocular melanoma | Genetic and Rare Diseases Information ...

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1/14/2013 · The Collaborative Ocular Melanoma Study or COMS for short, is a set of clinical trials designed to evaluate the treatments doctors use for their patients with choroidal melanoma. COMS clinical trials are funded by the National Eye Institute and the National Cancer Institute of the National Institutes of Health, and are being conducted at more ...

Ocular melanoma | Genetic and Rare Diseases Information ...

Ocular Melanoma - EyeWiki

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Local treatment rates are high after radiotherapy and enucleation. However, metastatic disease was diagnosed at a 25% and 34% rate at 5-years and 10-years respectively in the Collaborative Ocular Melanoma Study (COMS) with the liver affected 89% of the time.

Ocular Melanoma - EyeWiki

Clinical Trials - Ocular Melanoma

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Depending on the goals of the research, there are several different types of clinical trials: > Prevention trials look for better ways to reduce the risk of cancer in people who have never had it or to prevent a cancer from coming back.These methods may include medicines, vitamins, vaccines, or lifestyle changes.

Clinical Trials - Ocular Melanoma

THE JULES FRANÇOIS MEMORIAL LECTURE * THE COLLABORATIVE ...

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the Collaborative Ocular Melanoma Study, and forward-looking goals of choroidal melanoma research. The first major publication from a large, multicenter randomized clinical trial in ophthalmology was published in the American Journal of Ophthalmology in 1976, …

THE JULES FRANÇOIS MEMORIAL LECTURE * THE COLLABORATIVE ...

Collaborative Ocular Melanoma Study (COMS) randomized ...

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Collaborative Ocular Melanoma Study (COMS) randomized ...

Collaborative Ocular Melanoma Study (COMS) randomized ...

Radiation Oncology/Eye/Ocular melanoma - Wikibooks

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The Collaborative Ocular Melanoma Study (COMS) is a set of clinical trials that was carried out in 1980's - 1990's to evaluate the role of radiation therapy in management of ocular melanoma: Small tumors (height 1 - 3 mm, diameter >5 mm) were prospectively observed

Radiation Oncology/Eye/Ocular melanoma - Wikibooks

Uveal Melanoma: Diagnosis, Prognosis and Current ...

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Collaborative Ocular Melanoma Study (COMS) trials were designed. Funding was obtained from the National Eye Institute. In this review we sum-marize the main objectives, signi cant design features, and major ndings of the COMS. 18.1 Introduction The COMS was a multicentered study with 43 ...

Uveal Melanoma: Diagnosis, Prognosis and Current ...

Uveal Malignant Melanoma: 18 The Collaborative Ocular ...

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BALTIMORE — Mortality rates for patients with choroidal melanoma are comparable for both iodine 125 brachytherapy and enucleation, according to the Collaborative Ocular Melanoma Study (COMS).

Uveal Malignant Melanoma: 18 The Collaborative Ocular ...

Radiation, enucleation have comparable mortality rates in ...

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Collaborative Ocular Tuberculosis Study (COTS) - A global multicentre study of clinical features and factors affecting treatment outcome in intraocular tuberculosis – report 1 You will receive an email whenever this article is corrected, updated, or cited in the literature.

Radiation, enucleation have comparable mortality rates in ...

Collaborative Ocular Tuberculosis Study (COTS) - A global ...

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The proposed study is a multicenter, randomized, controlled clinical trial designed to compare enucleation of eyes with choroidal melanomas with irradiation on...

Collaborative Ocular Tuberculosis Study (COTS) - A global ...

Collaborative Ocular Melanoma Study - William Mieler

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What does COMS stand for? Definition of COMS in the Abbreviations.com acronyms and abbreviations directory.

Collaborative Ocular Melanoma Study - William Mieler

COMS - Collaborative Ocular Melanoma Study

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The Investigators' Perspective on the Collaborative Ocular Melanoma Study ...

COMS - Collaborative Ocular Melanoma Study

Ocular Melanoma: Johns Hopkins Sidney Kimmel Comprehensive ...

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The Collaborative Ocular Melanoma Study (COMS) The Collaborative Ocular Melanoma Study (COMS) includes two separate,long-term, multicenter, randomized controlled trials that comparetreatments and track the survival rate of patients with ocular melanoma.Collectively, …

Ocular Melanoma: Johns Hopkins Sidney Kimmel Comprehensive ...

The Investigators' Perspective on the Collaborative Ocular ...

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Collaborative Ocular Melanoma Study definition, categories, type and other relevant information provided by All Acronyms. COMS stands for Collaborative Ocular Melanoma Study

The Investigators' Perspective on the Collaborative Ocular ...
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